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Targeted alpha-particle therapy (or TAT) is an in-development method of targeted radionuclide therapy of various cancers. It employs radioactive substances which undergo alpha decay to treat diseased tissue at close proximity. [1] It has the potential to provide highly targeted treatment, especially to microscopic tumour cells.
Reflect the stage of cancer; By determining the stage of cancer, it's possible to give a prognosis and treatment plan. [3] Screening for cancers; No screening test is wholly specific, and a high level of tumor marker can still be found in benign tumors. The only tumor marker currently used in screening is PSA (prostate-specific antigen ...
As with most blood tests, false-negatives can happen, meaning results could come back negative when a cancer does exist — although Grail reports that negative cancer test results from Galleri ...
In addition to their use in cancer medicine, biomarkers are often used throughout the cancer drug discovery process. For instance, in the 1960s, researchers discovered the majority of patients with chronic myelogenous leukemia possessed a particular genetic abnormality on chromosomes 9 and 22 dubbed the Philadelphia chromosome .
The drug is also used in the evaluation of breast nodules. Malignant breast tissues concentrate 99m Tc MIBI to a much greater extent and more frequently than benign disease. As such, limited characterization of breast anomalies is possible. Scintimammography has a high sensitivity and specificity for breast cancer, both more than 85%. [7]
However, in the three-year study, both groups of breast cancer survivors were observed to have similar gray and white matter volumes. Altered brain structure in chemotherapy patients provides explanation for cognitive impairment. [12] Another study in 2007 investigated the differences in brain structure between two adult, monozygotic twin females.
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