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  2. Megaloblastic anemia - Wikipedia

    en.wikipedia.org/wiki/Megaloblastic_anemia

    Megaloblastic anemia is a type of macrocytic anemia. An anemia is a red blood cell defect that can lead to an undersupply of oxygen. [1] Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. [2] When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M ...

  3. Macrocytic anemia - Wikipedia

    en.wikipedia.org/wiki/Macrocytic_anemia

    Macrocytic anemias have several causes but with the implementation of folic acid fortification in North America, folate deficiency has become a rare cause of megaloblastic macrocytic anemia in that part of the world. [1] In this region, Vitamin B 12 deficiency is a far more common cause of megaloblastic macrocytic anemia. [1]

  4. Orotic aciduria - Wikipedia

    en.wikipedia.org/wiki/Orotic_aciduria

    Other names: Orotidylic pyrophosphorylase and orotidylic decarboxylase deficiency; Uridine monophosphate synthase (UMPS) deficiency [1] Structure of orotic acid: Specialty: Hematology Symptoms: Megaloblastic anemia; developmental delays: Causes: Autosomal recessive mutation of the UMPS gene: Differential diagnosis

  5. Dr. Jeff Hersh explains what causes anemia and options ... - AOL

    www.aol.com/dr-jeff-hersh-explains-causes...

    Other causes. The hematocrit is the ratio of the total volume of blood to the total volume of red blood cells, and is measured as part of a complete blood count. This is the primary test done to ...

  6. List of hematologic conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_hematologic_conditions

    Macrocytic anemia: Megaloblastic anemia: D51.1, D52.0, D53.1: 29507: Megaloblastic anemia (or megaloblastic anaemia) is an anemia of macrocytic classification that results from inhibition of DNA synthesis in red blood cell production. [10] Microangiopathic hemolytic anemia: Minkowski-Chauffard syndrome: Myelophthisic anemia: D61.9

  7. Hypersegmented neutrophil - Wikipedia

    en.wikipedia.org/wiki/Hypersegmented_neutrophil

    The presence of hypersegmented neutrophils is an important diagnostic feature of megaloblastic anaemias. Hypersegmentation can also be seen in many other conditions but with relatively less diagnostic significance. Hypersegmentation can sometimes be difficult to assert since interobserver variation is high and segmentation may vary with race.