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The most general and maintainable advice for treating peripheral neuropathy and mononeuropathy would be to lead a balanced and healthy lifestyle, without good nutrition, exercise, avoiding mass exposure to toxins, balanced intake and absorption of vitamins and minerals, and reducing one’s alcoholic and smoking frequency. [4]
Pregabalin and gabapentin may reduce pain associated with diabetic neuropathy. [28] [26] [29] [30] The anticonvulsants carbamazepine and oxcarbazepine are especially effective in trigeminal neuralgia. Carbamazepine is a voltage-gated sodium channel inhibitor, and reduces neuronal excitability by preventing depolarisation. [31]
It is a vitamin B supplement. Metanx is indicated for the dietary management of peripheral neuropathy (i.e. DPN). [1] ... Painful diabetic neuropathy, [3]
It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. [11] It is moderately effective: about 30–40% of those given gabapentin for diabetic neuropathy or postherpetic neuralgia have a meaningful benefit. [12]
Diabetes is the leading known cause of neuropathy in developed countries, and neuropathy is the most common complication and greatest source of morbidity and mortality in diabetes. A systematic review has found that diabetic peripheral neuropathy affects 30% of diabetes patients. [ 1 ]
Neuropathy can be due to chronic high blood sugar levels (diabetic neuropathy). These drugs also reduce pain from viruses such as shingles, phantom limb pain and post-stroke pain. [74] These mechanisms vary and in general are more effective in neuropathic pain disorders as well as complex regional pain syndrome. [75]