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Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.
Treatment for hemochromatosis type 3 may include reducing iron levels by removing blood (phlebotomy), iron chelation therapy, diet changes, and treatment for complications of the disease. The purpose of the treatment is to reduce the amount of iron in the body to normal levels, prevent or delay organ damage from excess iron, and maintain normal ...
Haemochromatosis is protean in its manifestations, i.e., often presenting with signs or symptoms suggestive of other diagnoses that affect specific organ systems.Many of the signs and symptoms below are uncommon, and most patients with the hereditary form of haemochromatosis do not show any overt signs of disease nor do they have premature morbidity, if they are diagnosed early, but, more ...
How to Reset Female Hormones For Weight Loss. This article was reviewed by Craig Primack, MD, FACP, FAAP, MFOMA. Hormones can be helpful heroes, supporting the immune system and a healthy sleep ...
The Basics of Losing Weight After 40. Losing weight can be challenging at the best of times. But after the big 4-0, a few more challenges pop up, making weight gain common and weight loss harder.
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This can lead to oxidative stress, lipid peroxidation, and DNA damage, which may result in cell death. [4] Two main forms of hemochromatosis type 4 exist (A and B), and the symptoms of these forms are distinct from one another. [3] Type 4A hemochromatosis typically has milder symptoms than other types of hemochromatosis.
Estrogen has a protective benefit to the heart and loss of it can impact some of the specific risk factors for heart health, which include high cholesterol, high blood pressure, and weight gain.