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Tendons and ligaments play an active role in maintain joint stability and controls the limits of joint movements, once injured tendons and ligaments detrimentally impact motor functions. [2] [8] Continuous exercise or movement of a musculoskeletal injury can result in chronic inflammation with progression to permanent damage or disability. [9]
Chronic systemic inflammation is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.It can contribute to the development or progression of certain conditions such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, autoimmune and neurodegenerative ...
Tendinitis is a type of overuse injury to the tendons, which demonstrates signs of inflammation of tendons around a joint. Tendinitis is the most common cause of shoulder pain and also leg pain . Tendinitis occurs when there is repetitive stress on the subacromial bursa, which causes the bones to make contact with the tendons and irritate them.
Painful joints can have a significant impact on quality of life and the ability to do daily activities. Joint pain is a common symptom we all experience at some point or another. Painful joints ...
Chronic pain has many pathophysiological and environmental causes and can occur in cases such as neuropathy of the central nervous system, after cerebral hemorrhage, tissue damage such as extensive burns, inflammation, autoimmune disorders such as rheumatoid arthritis, psychological stress such as headache, migraine or abdominal pain (caused by ...
Rheumatoid arthritis - autoimmune disease with an unclear cause that manifests as symmetric, erosive synovitis and, occasionally, extraarticular involvement. [19] Systemic lupus erythematosus - chronic, complex autoimmune inflammatory disorder that can affect every organ in the body. [20] Scleroderma - diverse collection of autoimmune fibrosing ...