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Common symptoms of chronic inflammation include fatigue, joint or muscle pain, long-lasting digestive issues, brain fog or difficulty concentrating, skin problems (like eczema or acne) and ...
Research reveals that long-term inflammation may lead to conditions like insulin resistance and possibly even type 2 diabetes. Conversely, certain health conditions may increase your risk of ...
ROS, alone, cause more than 20 types of DNA damage. [50] Oxidative DNA damages cause both mutations [51] and epigenetic alterations. [52] [46] [53] RNS also cause mutagenic DNA damages. [54] A normal cell may undergo carcinogenesis to become a cancer cell if it is frequently subjected to DNA damage during long periods of chronic inflammation ...
Inflammaging is thought to be caused by a loss of control over systemic inflammation resulting in chronic overstimulation of the innate immune system. Inflammaging is a significant risk factor in mortality and morbidity in aged individuals. [2] [3] [4] Inflammation is essential to protect against viral and bacterial infection, as well as ...
Chronic systemic inflammation is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.It can contribute to the development or progression of certain conditions such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, autoimmune and neurodegenerative ...
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