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With regard to morphology, the initial lesion that characterizes a condition is known as the "primary lesion", and identification of such a lesions is the most important aspect of the cutaneous examination. [30] Over time, these primary lesions may continue to develop or be modified by regression or trauma, producing "secondary lesions". [1]
A lentigo (/ l ɛ n ˈ t aɪ ɡ oʊ /) (plural lentigines, / l ɛ n ˈ t ɪ dʒ ɪ n iː z /) is a small pigmented spot on the skin with a clearly defined edge, surrounded by normal-appearing skin. It is a harmless (benign) hyperplasia of melanocytes which is linear in its spread.
The initial yaws wound contains infectious bacteria, which are passed onto others through skin-to-skin contact, typically during play or other normal childhood interactions. [10] [16] Early (primary and secondary) yaws lesions have a higher bacterial load, thus are more infectious. [2] Both papillomas and ulcers are infectious. [10]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Lesions are often classified by their tissue types or locations. For example, a "skin lesion" or a "brain lesion" are named for the tissue where they are found.If there is an added significance to regions within the tissue—such as in neural injuries where different locations correspond to different neurological deficits—they are further classified by location.
Diagnosis is by biopsy and analysis of any skin lesion that has signs of being potentially cancerous. [1] Avoiding UV light and using sunscreen in UV-bright sun conditions may prevent melanoma. [2] Treatment typically is removal by surgery of the melanoma and the potentially affected adjacent tissue bordering the melanoma. [1]
Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B 3). [2] Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. [1] Areas of the skin exposed to friction and radiation are typically affected first. [1]
The primary skin lesions in these patients vary, ranging from permanent maculopapular lesions to long-lasting plaque-like lesions, even though they may also present with urticarial lesions. Patients with coexisting wheals and plaques and who are pregnant are said to have pruritic urticarial papules and plaques of pregnancy (also called ...