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Billy Connolly (born 1942), Scottish comedian and actor. [13] Neil Diamond (born 1941), American singer. [14] Frank Elstner (born 1942), German television moderator and entertainer [15] Ranulph Fiennes (born 1944), British explorer and writer. [16] Michael J. Fox (born 1961), Canadian-American actor.
James Parkinson. Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease of mainly the central nervous system that affects both the motor and non-motor systems of the body. The symptoms usually emerge slowly, and, as the disease progresses, non-motor symptoms become more common. Usual symptoms include tremors, slowness ...
Parkinson's disease patient showing a typical flexed walking posture in advanced stage. Signs and symptoms of Parkinson's disease are varied. Parkinson's disease affects movement, producing motor symptoms. [1] Non-motor symptoms, which include dysautonomia, cognitive and neurobehavioral problems, and sensory and sleep difficulties, are also ...
A. Schematic initial progression of Lewy body deposits in the first stages of Parkinson's Disease, as proposed by Braak and colleagues. B. Localization of the area of significant brain volume reduction in initial PD compared with a group of participants without the disease in a neuroimaging study which concluded that brain stem damage may be the first identifiable stage of PD neuropathology. [1]
Frequency. 5 per 100,000 people. Multiple system atrophy (MSA) is a rare neurodegenerative disorder [1] characterized by tremors, slow movement, muscle rigidity, and postural instability (collectively known as parkinsonism), autonomic dysfunction and ataxia. This is caused by progressive degeneration of neurons in several parts of the brain ...
The University of Pennsylvania Smell Identification Test (UPSIT) is a test that is commercially available for smell identification to test the function of an individual's olfactory system. Known for its accuracy among smell identification tests it is considered to be one of the most reliable (r=.94) and trusted. [1]