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  2. Temozolomide - Wikipedia

    en.wikipedia.org/wiki/Temozolomide

    Temozolomide. 212 °C (414 °F) (decomp.) Temozolomide, sold under the brand name Temodar among others, is an anticancer medication used to treat brain tumors such as glioblastoma and anaplastic astrocytoma. [4][5] It is taken by mouth or via intravenous infusion. [4][5] The most common side effects with temozolomide are nausea, vomiting ...

  3. List of chemotherapeutic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_chemotherapeutic...

    This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer.This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.

  4. Alternating electric field therapy - Wikipedia

    en.wikipedia.org/wiki/Alternating_electric_field...

    Optune was approved by the FDA for newly diagnosed glioblastoma on Oct. 5, 2015, [31] as a result of randomized phase 3 trial results that reported a 3-month advantage in overall survival and progression-free survival when added to chemotherapy with temozolomide. [23] [24] In the US, Medicare covers treatment, as of February 2020. [32]

  5. Glioblastoma - Wikipedia

    en.wikipedia.org/wiki/Glioblastoma

    Glioblastoma, previously known as glioblastoma multiforme (GBM), is the most aggressive and most common type of cancer that originates in the brain, and has a very poor prognosis for survival. [6][7][8] Initial signs and symptoms of glioblastoma are nonspecific. [1] They may include headaches, personality changes, nausea, and symptoms similar ...

  6. Alkylating antineoplastic agent - Wikipedia

    en.wikipedia.org/wiki/Alkylating_antineoplastic...

    An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group (C n H 2n+1) to DNA. [1] Since cancer cells, in general, proliferate faster and with less error-correcting than healthy cells, cancer cells are more sensitive to DNA damage—such as being alkylated. Alkylating agents are used to ...

  7. Metronomic therapy - Wikipedia

    en.wikipedia.org/wiki/Metronomic_therapy

    Metronomic therapy. Metronomic therapy is a new type of chemotherapy in which anti-cancer drugs are administered in a lower dose than the maximum tolerated dose repetitively over a long period to treat cancers with fewer side effects. Metronomic therapy is shown to affect both tumor microenvironment and tumor cells to achieve its therapeutic ...