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Maltitol is a sugar alcohol (a polyol) used as a sugar substitute and laxative. It has 75–90% of the sweetness of sucrose (table sugar) and nearly identical properties, except for browning . It is used to replace table sugar because it is half as calorific , does not promote tooth decay, and has a somewhat lesser effect on blood glucose .
Non-small cell lung cancer, oesophageal cancer, uterine cervical cancer, head and neck cancer and urothelial cancer: Nephrotoxicity, myelosuppression and nausea and vomiting (30-90%). Oxaliplatin: IV: Reacts with DNA, inducing apoptosis, non-cell cycle specific. Colorectal cancer, oesophageal cancer and gastric cancer
Electrolyte solutions, while not true antidiarrheals, are used to replace lost fluids and salts in acute cases.; Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
It is still available to physicians for patients in emergency situations that are life-threatening or require hospitalization. [16] Prucalopride (brand name Resolor) is a current drug approved for use in the EU since October 15, 2009, [17] in Canada (brand name Resotran) since December 7, 2011, [18] and in the United States since December 2018.
A lower incidence of grade 2 or higher-grade diarrhea for the crofelemer group was seen than the control group during cycle 2 based on patient outcomes and investigator assessments - (9.0% vs. 33. ...
The extent of diarrhea is graded based on severity, from 1 to 5. Grade 1 diarrhea is defined by an increase in the number of stools below four per day (compared with baseline). Grade 2 diarrhea is defined by an increase of 4–6 bowel movements per day. Grade 3 diarrhea is defined by an increase by 7 or more bowel movements per day.