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Erythema toxicum neonatorum is a common, non-threatening rash in newborns. [ 1 ] [ 2 ] It appears in 40-70% of newborns within the first week of life, and it typically improves within 1–2 weeks. [ 2 ] [ 3 ] [ 4 ] It only occurs during the newborn period, but may appear slightly later in premature babies.
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Erythema toxicum neonatorum, neonatal cephalic pustulosis, transient neonatal pustular melanosis, folliculitis, miliaria and milia are often ruled out before diagnosis. [4] [7] Some experts consider neonatal cephalic pustulosis (NCP) a form of neonatal acne while others do not. [5] NCP presents with facial papules and pustules but no comedones.
Erythema toxicum neonatorum; Transient neonatal pustular melanosis; Miliaria pustulosa; Infantile acropustulosis; Eosinophilic pustular folliculitis; Acne neonatorum (neonatal acne) Benign neonatal cephalic pustulosis (also called neonatal malasezzia furfur pustulosis) Infantile generalized pustular psoriasis
Transient neonatal pustular melanosis (TNPM), also known as pustular melanosis, is a type of neonatal pustular eruption that is a transient rash common in newborns.It is vesiculopustular rash made up of 1–3 mm fluid-filled lesions that rupture, leaving behind a collarette of scale and a brown macule. [3]
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Other skin conditions that may appear similar include erythema toxicum neonatorum, transient neonatal pustular melanosis, infantile acne, miliaria, infantile acropustulosis, and sucking blisters. [3] CNS disease may appear like bacterial or other viral meningitis's. [3]