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Bladder stones or uroliths are a common occurrence in animals, especially in domestic animals such as dogs and cats. [1] Occurrence in other species, including tortoises, [2] has been reported as well. The stones form in the urinary bladder in varying size and numbers secondary to infection, dietary influences, and genetics.
It is a disease involving the defective transepithelial transport of cystine and dibasic amino acids in the kidney and intestine, and is one of many causes of kidney stones. If not treated properly, the disease could cause serious damage to the kidneys and surrounding organs, and in some rare cases death.
All forms of portosystemic shunts produce various neurological, gastrointestinal, and urinary symptoms. [3]Symptoms of congenital PSS usually appear by six months of age [4] and include failure to gain weight, vomiting, and signs of hepatic encephalopathy (a condition where toxins normally removed by the liver accumulate in the blood and impair the function of brain cells) such as seizures ...
Struvite urinary stones and crystals form readily in the urine of animals and humans that are infected with ammonia-producing organisms. They are potentiated by alkaline urine and high magnesium excretion (high magnesium/plant-based diets). They also are potentiated by a specific urinary protein in domestic cats.
15-20% of FLUTD cases are caused by uroliths ("stones") which occur when crystals which may be present in urine coalesce to form small stones. The most common types observed are struvite and calcium oxalate. [5] The majority of uroliths are located in the urinary bladder, but can also form in the kidneys, ureters and urethra.
Cystoscopy has similar indications in animals, including visualisation and biopsy of mucosa, retrieval or destruction of urinary bladder stones and diagnosis of ectopic ureters. [9] [10] [11] In turtle and tortoises, cystoscopy has additional value as it permits the visualisation of internal organs due to the thin urinary bladder wall. [12]
Some stones are too large even for cystoscopic treatment and may require open cystotomy, in which an incision is made in the bladder and the stones are removed manually. For children with urinary stones, the evidence supporting treatment options is very weak and high quality trials are necessary to help guide clinical management. [17]
Struvite (magnesium ammonium phosphate) stones removed from a dog's urinary bladder. Several factors contribute to the formation of renal stones in space. Dietary changes, bone metabolism, dehydration, increased salt intake as well as decreased urine volumes and increased urine saturation are all possible causes of renal stone formation. [2]