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In cell biology, single-cell variability occurs when individual cells in an otherwise similar population differ in shape, size, position in the cell cycle, or molecular-level characteristics. Such differences can be detected using modern single-cell analysis techniques. [ 1 ]
Functions involving two or more variables require multidimensional array indexing techniques. The latter case may thus employ a two-dimensional array of power[x][y] to replace a function to calculate x y for a limited range of x and y values. Functions that have more than one result may be implemented with lookup tables that are arrays of ...
This single cell shows the process of the central dogma of molecular biology, which are all steps researchers are interested to quantify (DNA, RNA, and Protein).. In cell biology, single-cell analysis and subcellular analysis [1] refer to the study of genomics, transcriptomics, proteomics, metabolomics, and cell–cell interactions at the level of an individual cell, as opposed to more ...
Although the 30 samples were all simulated under the null, one of the resulting p-values is small enough to produce a false rejection at the typical level 0.05 in the absence of correction. Multiple comparisons arise when a statistical analysis involves multiple simultaneous statistical tests, each of which has a potential to produce a "discovery".
More precisely, in multiple-instance learning, the training set consists of labeled "bags", each of which is a collection of unlabeled instances. A bag is positively labeled if at least one instance in it is positive, and is negatively labeled if all instances in it are negative. The goal of the MIL is to predict the labels of new, unseen bags.
Polyinstantiation in computer science is the concept of type (class, database row or otherwise) being instantiated into multiple independent instances (objects, copies). It may also indicate, such as in the case of database polyinstantiation, that two different instances have the same name (identifier, primary key).
Recursion that contains only a single self-reference is known as single recursion, while recursion that contains multiple self-references is known as multiple recursion. Standard examples of single recursion include list traversal, such as in a linear search, or computing the factorial function, while standard examples of multiple recursion ...
Detecting differences in gene expression level between two populations is used both single-cell and bulk transcriptomic data. Specialised methods have been designed for single-cell data that considers single cell features such as technical dropouts and shape of the distribution e.g. Bimodal vs. unimodal. [23]