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Ions can create excitatory or inhibitory potentials due to their unique reversal potentials and the membrane's permeability to each ion. The Nernst equation and Goldman equation can calculate membrane potential differences based on ion concentration, offering predictions into how ions can affect postsynaptic potentials. [3]
The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC). EPSPs, like IPSPs, are graded (i.e. they have an additive effect). When multiple EPSPs occur on a single patch of postsynaptic membrane, their combined effect is the sum of the individual EPSPs.
EPSPs on the postsynaptic neuron result from the main excitatory neurotransmitter, glutamate, binding to its corresponding receptors on the postsynaptic membrane. By contrast, IPSPs are induced by the binding of GABA(gamma-aminobutyric acid), or glycine. [4] Synaptic potentials are small and many are needed to add up to reach the threshold ...
ERPs are used extensively in neuroscience, cognitive psychology, cognitive science, and psycho-physiological research. Experimental psychologists and neuroscientists have discovered many different stimuli that elicit reliable ERPs from participants. The timing of these responses is thought to provide a measure of the timing of the brain's ...
The Induced current is the current generated in a wire due to change in magnetic flux. An example of the induced current is the current produced in the generator which involves rapidly rotating a coil of wire in a magnetic field. It is a qualitative law that
The current duration varies among publications, but is on the order of 0.1-5 seconds. However, this also implies that an injected current that did not result in spikes could have resulted in spikes if the duration was longer. For this reason, the current duration should be specified when reporting a cell's rheobase. Precision
The sweep technique is a hybrid frequency domain/time domain technique. [16] A plot of, for example, response amplitude versus the check size of a stimulus checkerboard pattern plot can be obtained in 10 seconds, far faster than when time-domain averaging is used to record an evoked potential for each of several check sizes. [16]
This induced voltage created by the changing current has the effect of opposing the change in current. This is stated by Lenz's law , and the voltage is called back EMF . Inductance is defined as the ratio of the induced voltage to the rate of change of current causing it. [ 1 ]