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  2. McDonald–Kreitman test - Wikipedia

    en.wikipedia.org/wiki/McDonald–Kreitman_test

    A slightly deleterious mutation can be defined as a mutation that negative selection acts on only very weakly so that its fate is determined by both selection and random genetic drift. [3] If slightly deleterious mutations are segregating in the population, then it becomes difficult to detect positive selection and the degree of positive ...

  3. Unit of selection - Wikipedia

    en.wikipedia.org/wiki/Unit_of_selection

    Two useful introductions to the fundamental theory underlying the unit of selection issue and debate, which also present examples of multi-level selection from the entire range of the biological hierarchy (typically with entities at level N-1 competing for increased representation, i.e., higher frequency, at the immediately higher level N, e.g., organisms in populations or cell lineages in ...

  4. Natural selection - Wikipedia

    en.wikipedia.org/wiki/Natural_selection

    However, after a period with no new mutations, the genetic variation at these sites is eliminated due to genetic drift. Natural selection reduces genetic variation by eliminating maladapted individuals, and consequently the mutations that caused the maladaptation. At the same time, new mutations occur, resulting in a mutationselection ...

  5. Negative selection (natural selection) - Wikipedia

    en.wikipedia.org/wiki/Negative_selection...

    This can result in stabilising selection through the purging of deleterious genetic polymorphisms that arise through random mutations. [2] [3] Purging of deleterious alleles can be achieved on the population genetics level, with as little as a single point mutation being the unit of selection. In such a case, carriers of the harmful point ...

  6. Genetic diversity - Wikipedia

    en.wikipedia.org/wiki/Genetic_diversity

    A mutation will increase genetic diversity in the short term, as a new gene is introduced to the gene pool. However, the persistence of this gene is dependent of drift and selection (see above). Most new mutations either have a neutral or negative effect on fitness, while some have a positive effect. [11]

  7. Outline of evolution - Wikipedia

    en.wikipedia.org/wiki/Outline_of_evolution

    Genetic hitchhiking – Phenomenon in biology; Negative selection (natural selection) – Selective removal of alleles that are deleterious; Related topics Microevolution – Change in allele frequencies that occurs over time within a population; Evolutionary game theory – Application of game theory to evolving populations in biology

  8. Glossary of genetics and evolutionary biology - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_genetics_and...

    Also called functionalism. The Darwinian view that many or most physiological and behavioral traits of organisms are adaptations that have evolved for specific functions or for specific reasons (as opposed to being byproducts of the evolution of other traits, consequences of biological constraints, or the result of random variation). adaptive radiation The simultaneous or near-simultaneous ...

  9. Genetic variation - Wikipedia

    en.wikipedia.org/wiki/Genetic_variation

    Random mutations are the ultimate source of genetic variation. Mutations are likely to be rare, and most mutations are neutral or deleterious, but in some instances, the new alleles can be favored by natural selection. Polyploidy is an example of chromosomal mutation. Polyploidy is a condition wherein organisms have three or more sets of ...