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Florbetaben, sold under the brand name Neuraceq, is a diagnostic radiotracer developed for routine clinical application to visualize β-amyloid plaques in the brain. It is a fluorine-18 ( 18 F)-labeled stilbene derivative.
Florbetapir (18 F), sold under the brand name Amyvid, is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18 that was approved for use in the United States in 2012, [4] as a diagnostic tool for Alzheimer's disease.
The advantage of 18F-FDG PET for these uses is its much wider availability. Some radioactive tracers used for Alzheimer's are florbetapir 18F, flutemetamol F18, PiB and florbetaben 18F, which are all used to detect amyloid-beta plaques (a potential biomarker for Alzheimer's) in the brain.
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Of the 176 patients imaged in this trial had a median age was 82, with 57 of patients being female. The initial flutemetamol PET scan resulted in 43 positive and 25 negative results for cerebral cortisol amyloid status. 69 of the initial patients died within 13 months of the flutemetamol PET scan.
Fluoroethyl-l-tyrosine (18 F) commonly known as [18 F]FET, is a radiopharmaceutical tracer used in positron emission tomography (PET) imaging.This synthetic amino acid, labeled with the radioactive isotope fluorine-18, is a valuable radiopharmaceutical tracer for use in neuro-oncology for diagnosing, planning treatment, and following up on brain tumors such as gliomas.
Flortaucipir (18 F) is a radioactive diagnostic agent for adults with cognitive impairment who are being evaluated for Alzheimer's disease. [1]It is indicated for positron emission tomography (PET) imaging of the brain to estimate the density and distribution of aggregated tau neurofibrillary tangles (NFTs), a primary marker of Alzheimer's disease.