Search results
Results From The WOW.Com Content Network
Longer TATA box sequences correlates with higher levels of PG2 serum indicating gastric cancer conditions. Carriers with shorter TATA box sequences may produce lower levels of PG2 serum. Several neurodegenerative disorders are associated TATA box mutations. [40] Two disorders have been highlighted, spinocerebellar ataxia and Huntington's disease.
The TATA-binding protein (TBP) is a general transcription factor that binds to a DNA sequence called the TATA box. This DNA sequence is found about 30 base pairs upstream of the transcription start site in some eukaryotic gene promoters .
The archaeal promoter resembles an eukaryotic one: a TATA box (at -26/-27) and an upstream BRE (at -33/-34) are commonly found, binding to TBP and TFB (homolog of TFIIB). [3] There are also occasionally an initiator element (INR) near the transcription start site [TSS], and a promoter proximal element (PPE) between BRE-TATA and TSS.
A common basal promoter is the TATAAAAAA sequence known as the TATA box. The TATA box is a complex with several different proteins including transcription factor II D (TFIID) which includes the TATA-binding protein (TBP) that binds to the TATA box along with 13 other proteins that bind to TBP. The TATA box binding proteins also include the ...
107182 Ensembl ENSG00000095564 ENSMUSG00000040565 UniProt O14981 Q2M1V9 E9QAE3 RefSeq (mRNA) NM_003972 NM_001080706 RefSeq (protein) NP_003963 NP_003963.1 NP_001074175 Location (UCSC) Chr 10: 91.92 – 92.03 Mb Chr 19: 36.9 – 36.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse TATA-binding protein-associated factor 172 is a protein that in humans is encoded by the BTAF1 gene ...
TATA-box binding protein like 2 is a protein that in humans is encoded by the TBPL2 gene. [5] The TBPL2 protein is also known as TBP-related factor 3 (TRF3) and TATA binding protein 2 (TBP2). The protein was independently discovered in three laboratories as a vertebrate-specific family member of TATA-binding protein (TBP).
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa, also known as TAF9, is a protein that in humans is encoded by the TAF9 gene. [5] [6]
The TATA box is one well-studied example of a promoter element that occurs in approximately 10% of genes. It is conserved in many (though not all) model eukaryotes and is found in a fraction of the promoters in these organisms. The sequence TATA (or variations) is located at approximately 25 nucleotides upstream of the Transcription Start Point ...