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Spondyloarthritis (SpA), also known as spondyloarthropathy, is a collection of clinical syndromes that are connected by genetic predisposition and clinical manifestations. [1] The best-known clinical subtypes are enteropathic arthritis (EA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and reactive arthritis (ReA). [ 2 ]
Enthesopathy of the pelvis likely due to ankylosing spondylitis Enthesopathy can occur at the shoulder, elbow, wrist, carpus , hip, knee, ankle, tarsus , or heel bone , among other regions. Enthesopathies may take the form of spondyloarthropathies (joint diseases of the spine) such as ankylosing spondylitis , or psoriatic arthritis , plantar ...
Enthesitis is inflammation of the entheses (singular: enthesis), the sites where tendons, ligaments and joint capsules attach to bones. [1] [2]It is a type of enthesopathy, meaning any pathologic condition of the entheses, with or without inflammation.
A disease of the entheses is known as an enthesopathy or enthesitis. [5] Enthetic degeneration is characteristic of spondyloarthropathy and other pathologies. The enthesis is the primary site of disease in ankylosing spondylitis.
Psoriatic arthritis, [32] [33] enthesopathy linked to spondyloarthropathy, [34] and refractory ankylosing spondylitis [35] can all benefit from biological blockade using the TNFa antagonists etanercept and infliximab. Infliximab is also useful in reducing spondyloarthropathy and intestinal inflammation in Crohn's disease patients. [36]
Menopause is one risk factor for osteoarthritis. One recent study in mice uncovered that menopause led to a drop in 17beta-estradiol and progesterone, which increased cartilage aging, degeneration ...
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Seronegative spondyloarthropathy: Psoriatic arthritis; Ankylosing spondylitis; Rheumatoid arthritis: Felty's syndrome; Juvenile idiopathic arthritis; Adult-onset Still's disease; Crystal arthropathy; Gout; Chondrocalcinosis; Osteoarthritis; Hemarthrosis (joint bleeding) Synovitis is the medical term for inflammation of the synovial membrane ...