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Praziquantel is well absorbed (about 80%) from the gastrointestinal tract. However, due to extensive first-pass metabolism, only a relatively small amount enters systemic circulation. Praziquantel has a serum half-life of 0.8 to 1.5 hours in adults with normal renal and liver function. Metabolites have a half-life of 4 to 5 hours.
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Arpraziquantel ((R)-praziquantel) is the eutomer (the biologically active enantiomer) of praziquantel, and is a medication which is currently under investigation for the treatment of schistosomiasis in young children since it has less side effects than the usual racemic mixture formulation of praziquantel.
The petition filed by over 20 consumer advocacy groups in 2022 that argued for the removal of Red Dye No. 3 from food and dietary supplements cited studies, the FDA's prior use of the Delaney ...
Medicare’s drug pricing negotiations — the first of their kind in the United States, passed under President Joe Biden — face an uncertain future in the incoming Trump administration.
One of the best post-Christmas sales we look forward to every year is Nordstrom's Half-Yearly Sale, which typically kicks off the day after Christmas and lasts for a couple of weeks.Ring in the ...