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This is likely because the brain enters into a hypodopaminergic state, although there might be a role for noradrenaline also. For these drugs to be reinforcing, they must block more than 50% of the DAT within a relatively short time period (<15 minutes from administration) and clear the brain rapidly to enable fast repeated administration.
Burrrprint 2 (also stylized as Burrrprint (2) HD) is a mixtape by rapper Gucci Mane. It was released three months after the release of his fourth studio album The State vs. Radric Davis on March 13, 2010. [5] It is the sequel to The Burrprint mixtape released in 2009. Drumma Boy produced all but five songs on the mixtape. These songs were ...
The trisynaptic circuit or trisynaptic loop is a relay of synaptic transmission in the hippocampus.The trisynaptic circuit is a neural circuit in the hippocampus, which is made up of three major cell groups: granule cells in the dentate gyrus, pyramidal neurons in CA3, and pyramidal neurons in CA1.
"Reptilian complex" (also known as the "R-complex", "reptilian brain" or "lizard brain") was the name MacLean gave to the basal ganglia, structures derived from the floor of the forebrain during development. The term derives from the idea that comparative neuroanatomists once believed that the forebrains of reptiles and birds were dominated by ...
The inferior frontal gyrus is highly convoluted and has three cytoarchitecturally diverse regions. [2] The three subdivisions are an opercular part, a triangular part, and an orbital part. These divisions are marked by two rami arising from the lateral sulcus. [3] The ascending ramus separates the opercular and triangular parts. [4]
It is important in mediating saccadic eye movements. [2] It is probably not involved in smooth pursuit. [2] The PPRF generates excitatory bursts that are delivered to the ipsilateral abduecens nucleus to drive ipsilateral saccades (inhibitory saccadic stimuli are meanwhile delivered to the abducens nucleus from the contralateral medulla oblongata).
The placement of a repressive mark on lysine 27 requires the recruitment of chromatin regulators by transcription factors.These modifiers are either histone modification complexes which covalently modify the histones to move around the nucleosomes and open the chromatin, or chromatin remodelling complexes which involve movement of the nucleosomes without directly modifying them. [4]
The parietal lobe is located directly behind the central sulcus, superior to the occipital lobe and posterior to the frontal lobe, visually at the top of the back of the head. [18] The make up of the parietal lobe is defined by four anatomical boundaries in the brain, providing a division of all the four lobes. [18]