Search results
Results From The WOW.Com Content Network
The two main fluid compartments are the intracellular and extracellular compartments. The intracellular compartment is the space within the organism's cells; it is separated from the extracellular compartment by cell membranes. [1] About two-thirds of the total body water of humans is held in the cells, mostly in the cytosol, and the remainder ...
In cell biology, molecular biology and related fields, the word extracellular (or sometimes extracellular space) means "outside the cell". This space is usually taken to be outside the plasma membranes, and occupied by fluid (see extracellular matrix). The term is used in contrast to intracellular (inside the cell).
Differences in the concentrations of ions giving the membrane potential. There is a significant difference between the concentrations of sodium and potassium ions inside and outside the cell. The concentration of sodium ions is considerably higher in the extracellular fluid than in the intracellular fluid. [23]
The pump has three effects: (1) it makes the sodium concentration high in the extracellular space and low in the intracellular space; (2) it makes the potassium concentration high in the intracellular space and low in the extracellular space; (3) it gives the intracellular space a negative voltage with respect to the extracellular space.
Intracellular pH is typically lower than extracellular pH due to lower concentrations of HCO 3 −. [9] A rise of extracellular (e.g., serum) partial pressure of carbon dioxide (pCO 2) above 45 mmHg leads to formation of carbonic acid, which causes a decrease of pH i as it dissociates: [10]
The total body of water is divided into fluid compartments, [1] between the intracellular fluid compartment (also called space, or volume) and the extracellular fluid (ECF) compartment (space, volume) in a two-to-one ratio: 28 (28–32) liters are inside cells and 14 (14–15) liters are outside cells.
These receptors have extracellular, trans-membrane and intracellular domains. The extracellular domain is responsible for the interaction with a specific ligand. The intracellular domain is responsible for the initiation of a cascade of chemical reactions which ultimately triggers the specific cellular function controlled by the receptor.
Moreover, in tissues with unequal anisotropy ratios, the ratio of conductivities parallel and perpendicular to the fibers are different in the intracellular and extracellular spaces. For instance, in cardiac tissue, the anisotropy ratio in the intracellular space is about 10:1, while in the extracellular space it is about 5:2. [13]