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In chemistry, a precursor is a compound that participates in a chemical reaction that produces another compound. In biochemistry , the term "precursor" often refers more specifically to a chemical compound preceding another in a metabolic pathway , such as a protein precursor .
Drug precursors, also referred to as precursor chemicals or simply precursors, are substances used to manufacture illicit drugs. Most precursors also have legitimate commercial uses and are legally used in a wide variety of industrial processes and consumer products, such as medicines, flavourings, and fragrances.
In cell biology, precursor cells—also called blast cells—are partially differentiated, or intermediate, and are sometimes referred to as progenitor cells. A precursor cell is a stem cell with the capacity to differentiate into only one cell type, meaning they are unipotent stem cells .
IMP is then converted to either a precursor to AMP or GMP. Once AMP or GMP are formed, they can be phosphorylated by ATP to their diphosphate and triphosphate forms. [23] Purine synthesis is regulated by the allosteric inhibition of IMP formation by the adenine or guanine nucleotides. [24]
In biochemistry, a zymogen (/ ˈ z aɪ m ə dʒ ən,-m oʊ-/ [1] [2]), also called a proenzyme (/ ˌ p r oʊ ˈ ɛ n z aɪ m / [3] [4]), is an inactive precursor of an enzyme.A zymogen requires a biochemical change (such as a hydrolysis reaction revealing the active site, or changing the configuration to reveal the active site) for it to become an active enzyme.
Proinsulin is the prohormone precursor to insulin made in the beta cells of the Pancreatic Islets, specialized regions of the pancreas. In humans, proinsulin is encoded by the INS gene. [1] [2] The pancreatic islets only secrete between 1% and 3% of proinsulin intact. [3]
A protein precursor, also called a pro-protein or pro-peptide, is an inactive protein (or peptide) that can be turned into an active form by post-translational modification, such as breaking off a piece of the molecule or adding on another molecule. The name of the precursor for a protein is often prefixed by pro-.
Ergosterol is a biological precursor of vitamin D 2, the chemical name of which is ergocalciferol. Exposure of white button mushrooms to UV-C irradiation produces time-dependent increases in vitamin D2 concentrations in the mushrooms.