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  2. Pantoprazole - Wikipedia

    en.wikipedia.org/wiki/Pantoprazole

    Pantoprazole has been found to pass through the breast milk. Additionally, in rodent cancer studies, pantoprazole has been shown to potentially cause tumor growth. The clinical relevance of the finding is unknown, but risks and benefits are recommended for consideration in determining the use of therapy for the mother and child. [15] [2]

  3. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Pantoprazole was identified after nearly seven years of research and registered for clinical use after a further seven years of development, and finally reached its first market in 1994 in Germany. During the course of the studies on pantoprazole, more than 650 PPIs had been synthesized and evaluated. [ 5 ]

  4. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Specialty professional organizations recommend that people take the lowest effective PPI dose to achieve the desired therapeutic result when used to treat gastroesophageal reflux disease long-term. [ 20 ] [ 21 ] [ 22 ] In the United States, the Food and Drug Administration (FDA) has advised that over-the-counter PPIs, such as Prilosec OTC ...

  5. Is There a "Best Time" to Take Metformin? - AOL

    www.aol.com/best-time-metformin-115700262.html

    First up, it’s super important to follow your healthcare provider’s instructions on when to take metformin. If you’ve been told a time to take your medication, stick with it. If you haven ...

  6. Drinking coffee at a certain time of day could reduce death ...

    www.aol.com/drinking-coffee-certain-time-day...

    "Moderate coffee drinking has been related to health benefits," lead study author Lu Qi, M.D., PhD, interim chair of the Department of Epidemiology at Tulane University, told Fox News Digital.

  7. Why you shouldn’t drink coffee first thing in the morning ...

    www.aol.com/article/lifestyle/2019/08/22/why-you...

    There are a few reasons why drinking coffee first thing in the morning isn't good and it ... your best bet is to pour yourself a cup after breakfast, between 9:30 a.m. and noon, a window when your ...

  8. Coffee could be more than a morning pick-me-up ... - AOL

    www.aol.com/drinking-1-3-cups-coffee-132218461.html

    Three cups of coffee or tea daily reduced risk of new onset cardiometabolic multimorbidity such as coronary heart disease, stroke and type 2 diabetes by 48.1%, according to a new study.

  9. Rectal administration - Wikipedia

    en.wikipedia.org/wiki/Rectal_administration

    The reasons for rectal administration are largely the same as with medicinal drugs: Bypassing the first-pass effect, fast onset, and a relatively high bioavailability with some drugs. [ 7 ] Rectal administration is sometimes thought of as a safer alternative to intravenous injection of psychoactive substances, [ 8 ] which carries a significant ...