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The American Cancer Society also stated that "natural" and "bioidentical" hormones present the same risks as synthetic hormone replacement therapy such as heart disease, blood clots, strokes and an increased risk of breast cancer with long-term use. [52]
Moreover, breast cancer risk is heightened following use of the combined oral contraceptive pill and combined hormone replacement therapy. [4] Armed with this evidence that endogenous and exogenous changes in estrogen and progesterone levels modulate the risk of breast cancer, it is apparent that hormones can play a key role in breast cancer.
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
[45] [46] It is of unclear effect in hot flashes in people with breast cancer. [47] The effects of aromatherapy are unclear with no peer-reviewed research in regards to cancer treatment. [48] Psychotherapy may reduce anxiety and improve quality of life as well as allow for improving patient moods. [23] Massage therapy may temporarily reduce ...
Estrogen deprivation therapy, also known as endocrine therapy, is a form of hormone therapy that is used in the treatment of breast cancer.Modalities include antiestrogens or estrogen blockers such as selective estrogen receptor modulators (SERMs) like tamoxifen, selective estrogen receptor degraders like fulvestrant, and aromatase inhibitors like anastrozole and ovariectomy.
Y-ME was founded in 1978 by breast cancer patients Ann Marcou (1932–2004) [6] and Mimi Kaplan (d. 1983), [7] and began as a hotline operated out of Marcou's Chicago-area home and a support group that met at a local YWCA. [7]
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