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Studies have proven that high-dose usage of aspirin can be associated with ototoxicity, manifesting reversible hearing loss and tinnitus. [20] The underlying mechanism is associated with a change in isolated cochlear outer hair cells (OHCs). Due to the COX inhibition, there is an increasing amount of leukotrienes in the inner ear. This ...
The hearing loss caused by chemicals can be very similar to a hearing loss caused by excessive noise. A 2018 informational bulletin by the US Occupational Safety and Health Administration (OSHA) and the National Institute for Occupational Safety and Health (NIOSH) introduces the issue, provides examples of ototoxic chemicals, lists the ...
Cefalexin, also spelled cephalexin, is an antibiotic that can treat a number of bacterial infections. [4] It kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. [ 4 ]
In children, hearing problems can affect the ability to acquire spoken language, and in adults it can create difficulties with social interaction and at work. [8] Hearing loss can be temporary or permanent. Hearing loss related to age usually affects both ears and is due to cochlear hair cell loss. [9]
Hearing loss due to chemicals starts in the high-frequency range and is irreversible. It damages the cochlea with lesions and degrades central portions of the auditory system. [45] For some ototoxic chemical exposures, particularly styrene, [46] the risk of hearing loss can be higher than being exposed to noise alone.
Prelingual hearing loss can be considered congenital, present at birth, or acquired, occurring after birth before the age of one. Congenital hearing loss can be a result of maternal factors (rubella, cytomegalovirus, or herpes simplex virus, syphilis, diabetes), infections, toxicity (pharmaceutical drugs, alcohol, other drugs), asphyxia, trauma, low birth weight, prematurity, jaundice, and ...
Language deprivation in deaf and hard-of-hearing children is a delay in language development that occurs when sufficient exposure to language, spoken or signed, is not provided in the first few years of a deaf or hard of hearing child's life, often called the critical or sensitive period. Early intervention, parental involvement, and other ...
Complete loss of the stereocilia causes permanent hearing damage and is more associated with noise-induced hearing loss and other auditory diseases. The outer hair cells, or OHCs, can be thought of as microamplifiers that provide stimulation to the inner hair cells. The OHCs are the most fragile of the hair cells, hence their involvement in ...