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  2. Melatonin - Wikipedia

    en.wikipedia.org/wiki/Melatonin

    Rather, melatonin performs important roles in plants as a growth regulator, as well as environmental stress protector. It is synthesized in plants when they are exposed to both biological stresses, for example, fungal infection, and nonbiological stresses such as extremes of temperature, toxins, increased soil salinity, drought, etc. [36] [87] [88]

  3. Light effects on circadian rhythm - Wikipedia

    en.wikipedia.org/wiki/Light_effects_on_circadian...

    Other factors such as music and properly timed administration of the neurohormone melatonin have shown similar effects. [29] [30] Numerous other factors affect entrainment as well. These include feeding schedules, temperature, pharmacology, locomotor stimuli, social interaction, sexual stimuli and stress. [31]

  4. Environmental impact of pharmaceuticals and personal care ...

    en.wikipedia.org/wiki/Environmental_impact_of...

    "The U.S. EPA risk assessment states that the acceptable daily intake (ADI) of pharmaceuticals is around 0.0027 mg/kg‐day." [citation needed] Due to the lack of research of toxicity guidelines and their effects on human health it is difficult to determine a healthy dosage for water contaminated by pharmaceuticals. "The pharmaceutical sample ...

  5. Sleep - Wikipedia

    en.wikipedia.org/wiki/Sleep

    If an entrained human is isolated in a bunker with constant light or darkness, he or she will continue to experience rhythmic increases and decreases of body temperature and melatonin, on a period that slightly exceeds 24 hours. Scientists refer to such conditions as free-running of the circadian rhythm. Under natural conditions, light signals ...

  6. 10 great nutritional supplements for winter - AOL

    www.aol.com/10-great-nutritional-supplements...

    Melatonin promotes healthy sleep while also supporting immune function. Sun exposure in the morning plays an important part in keeping our circadian rhythm in tune and contributes to melatonin ...

  7. Phase response curve - Wikipedia

    en.wikipedia.org/wiki/Phase_response_curve

    This is known as dim-light melatonin onset, DLMO. [12] This stimulates the phase-advance portion of the PRC and helps keep the body on a regular sleep-wake schedule. It also helps prepare the body for sleep. Administration of melatonin at any time may have a mild hypnotic (sleep-inducing) effect. The expected effect on sleep phase timing, if ...

  8. Chronotype - Wikipedia

    en.wikipedia.org/wiki/Chronotype

    They note that morning types evidence a more rapid decline in melatonin levels after the peak than do evening types. Baehr et al. [27] found that, in young adults, the daily body temperature minimum occurred at about 4 a.m. for morning types but at about 6 a.m. for evening types. This minimum occurred at approximately the middle of the eight ...

  9. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    Melatonin can lower follicle-stimulating hormone levels. [52] Melatonin's effects on human reproduction remain unclear. [53] Some supplemental melatonin users report an increase in vivid dreaming. Extremely high doses of melatonin increased REM sleep time and dream activity in people both with and without narcolepsy. [54]