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Δ-8-tetrahydrocannabinol (delta-8-THC, [a] Δ 8-THC) is a psychoactive cannabinoid found in the cannabis plant. [1] It is an isomer of delta-9-tetrahydrocannabinol (delta-9-THC, Δ 9 -THC), the compound commonly known as THC, with which it co-occurs in hemp ; natural quantities of ∆ 8 -THC found in hemp are low.
11-Hydroxy-Δ-8-tetrahydrocannabinol (11-OH-Δ 8-THC, alternatively numbered as 7-OH-Δ 6-THC) is an active metabolite of Δ 8-THC, a psychoactive cannabinoid found in small amounts in cannabis. It is an isomer of 11-OH-Δ 9-THC, and is produced via the same metabolic pathway. It was the first cannabinoid metabolite discovered in 1970. [1]
Tetrahydrocannabiphorol (THCP) is a potent phytocannabinoid, a CB 1 and CB 2 receptor agonist which was known as a synthetic homologue of tetrahydrocannabinol (THC), [1] but for the first time in 2019 was isolated as a natural product in trace amounts from Cannabis sativa.
1,2-Didehydro-3-oxo-THCO (1,2-Didehydro-3-oxo-Δ 8-tetrahydrocannabioctyl) is a semi-synthetic cannabinoid first synthesised by Raj K Razdan et al. in the 1970s, with potent cannabinoid effects. [ 1 ] [ 2 ] [ 3 ]
Cannabinoids (/ k ə ˈ n æ b ə n ɔɪ d z ˌ ˈ k æ n ə b ə n ɔɪ d z /) are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. [1] [2] The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis.
Isotetrahydrocannabinol (iso-THC or Δ8-Isotetrahydrocannabinol) is a phytocannabinoid similar in structure to cannabicitran which has been identified as a trace component of Cannabis, but is more commonly found as an impurity in synthetic THC which has been made from cannabidiol. iso-THC is present with other isomers with the double bond in a different position and the saturated dihydro ...
JWH-138 (THC-Octyl, Δ 8-THC-C8) is a synthetic cannabinoid first synthesized by Roger Adams and studied heavily by John W. Huffman, with a K i of 8.5nM at the CB 1 cannabinoid receptor. [1] THC-Octyl and its hydrogenated analog HHC-Octyl was synthesized and studied by Roger Adams as early as 1942.
Δ-11-Tetrahydrocannabinol (Delta-11-THC, Δ 11-THC, Δ 9(11)-THC, exo-Tetrahydrocannabinol) is a rare isomer of tetrahydrocannabinol, developed in the 1970s. It can be synthesised from Δ 8 -THC by several different routes, [ 1 ] [ 2 ] [ 3 ] though only the (6aR, 10aR) enantiomer is known.