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Bexagliflozin, sold under the brand name Bexacat, is an antidiabetic medication used to improve glycemic control in cats with diabetes. [2] Bexacat is the first sodium-glucose cotransporter 2 (SGLT2) inhibitor new animal drug approved by the US Food and Drug Administration (FDA) in any animal species. [ 2 ]
In cats with type 2 diabetes, prompt effective treatment may lead to diabetic remission, in which the cat no longer needs injected insulin. Untreated, the condition leads to increasingly weak legs in cats and eventually to malnutrition, ketoacidosis and/or dehydration, and death. Diabetes in cats can be classified into the following:
The vast majority of cats present with diabetes mellitus, the possibility of hypersomatotropism causing it is rarely considered until the diabetes becomes difficult to control. In cats with difficult to control diabetes mellitus, hypersomatotropism should be considered as a cause only after exclusion of other conditions that can impact insulin.
Capromorelin, sold under the brand names Entyce and Elura, is a medication used for the management of weight loss in cats and dogs. [5] [6] Capromorelin is a ghrelin receptor agonist known to increase appetite and weight gain. [2] Capromorelin was developed by Pfizer. [7] [8] Capromorelin was approved for veterinary use in the United States in ...
It may resolve with treatment of the diabetes. [8] The pathology of this condition in cats has been shown to be very similar to diabetic neuropathy in humans. [9] Distal symmetric polyneuropathy symptoms include atrophy of the distal leg muscles and the muscles of the head, and rear limb weakness. No treatment is known and the prognosis is poor.
Cats may be poisoned by many chemicals usually considered safe by their human guardians, [citation needed] because their livers are less effective at some forms of detoxification. [31] [32] Some of the most common causes of poisoning in cats are antifreeze and rodent baits. [33] Cats may be particularly sensitive to environmental pollutants. [34]