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  2. Pharmacodynamics - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics

    Toxicodynamics (TD) and pharmacodynamics (PD) link a therapeutic agent or toxicant, or toxin (xenobiotic)'s dosage to the features, amount, and time course of its biological action. [11] The mechanism of action is a crucial factor in determining effect and toxicity of the drug, taking in consideration the pharmacokinetic (PK) factors. [12]

  3. Mechanism of action - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action

    The mechanism of action of aspirin involves irreversible inhibition of the enzyme cyclooxygenase; [17] therefore suppressing the production of prostaglandins and thromboxanes, thus reducing pain and inflammation. This mechanism of action is specific to aspirin and is not constant for all nonsteroidal anti-inflammatory drugs (NSAIDs). Rather ...

  4. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    The pharmacodynamics of spironolactone, an antimineralocorticoid and antiandrogen medication, concern its mechanisms of action, including its biological targets and activities, as well as its physiological effects. The pharmacodynamics of spironolactone are characterized by high antimineralocorticoid activity, moderate antiandrogenic activity ...

  5. Pharmacology - Wikipedia

    en.wikipedia.org/wiki/Pharmacology

    D010600. Pharmacology is the science of drugs and medications, [1] including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. [2]

  6. Drug action - Wikipedia

    en.wikipedia.org/wiki/Drug_action

    The action of drugs on the human body (or any other organism's body) is called pharmacodynamics, and the body's response to drugs is called pharmacokinetics. The drugs that enter an individual tend to stimulate certain receptors, ion channels, act on enzymes or transport proteins. As a result, they cause the human body to react in a specific ...

  7. Midodrine - Wikipedia

    en.wikipedia.org/wiki/Midodrine

    Midodrine, sold under the brand names ProAmatine and Orvaten among others, is a vasopressor or antihypotensive medication used to treat orthostatic hypotension (low blood pressure when standing) and urinary incontinence. [3][5][1] It is taken by mouth. [3][1] Side effects of midodrine include hypertension (high blood pressure), paresthesia ...

  8. Mode of action - Wikipedia

    en.wikipedia.org/wiki/Mode_of_action

    A mechanism of action of a chemical could be "binding to DNA" while its broader mode of action would be "transcriptional regulation". [3] However, there is no clear consensus and the term mode of action is also often used, especially in the study of pesticides, to describe molecular mechanisms such as action on specific nuclear receptors or ...

  9. Pharmacodynamics of progesterone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Pharmacodynamics of progesterone. The pharmacology of progesterone, a progestogen medication and naturally occurring steroid hormone, concerns its pharmacodynamics, pharmacokinetics, and various routes of administration. [1][2] Progesterone is a naturally occurring and bioidentical progestogen, or an agonist of the progesterone receptor, the ...