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  2. Methyldiazonium - Wikipedia

    en.wikipedia.org/wiki/Methyldiazonium

    Methyldiazonium is an organic compound consisting of a methyl group attached to a diazo group.This cation is the conjugate acid of diazomethane, with an estimated pK a <10. [1]It is an intermediate in methylation reactions of diazomethane with acidic hydroxyl compounds, such as conversion of carboxylic acids to methyl esters and phenols to methyl ethers.

  3. Diazo - Wikipedia

    en.wikipedia.org/wiki/Diazo

    This reaction is also called the Regitz diazo transfer. [7] Examples are the synthesis of tert-butyl diazoacetate [ 8 ] and diazomalonate. [ 9 ] Methyl phenyldiazoacetate is generated in this way by treating methyl phenylacetate with p-acetamidobenzenesulfonyl azide in the presence of base.

  4. Nitrous acid - Wikipedia

    en.wikipedia.org/wiki/Nitrous_acid

    2) is a weak and monoprotic acid known only in solution, in the gas phase, and in the form of nitrite (NO − 2) salts. [3] It was discovered by Carl Wilhelm Scheele, who called it "phlogisticated acid of niter". Nitrous acid is used to make diazonium salts from amines. The resulting diazonium salts are reagents in azo coupling reactions to ...

  5. Demjanov rearrangement - Wikipedia

    en.wikipedia.org/wiki/Demjanov_rearrangement

    The reaction process begins with diazotization of the amine by nitrous acid. The diazonium group is a good leaving group, forming nitrogen gas when displaced from the organic structure. This displacement can occur via a rearrangement (path A), in which one of the sigma bonds adjacent to the diazo group migrates. This migration results in an ...

  6. Diazonium compound - Wikipedia

    en.wikipedia.org/wiki/Diazonium_compound

    The reaction of the surface with a solution of diazonium salt in acetonitrile for 2 hours in the dark is a spontaneous process through a free radical mechanism: [42] Diazonium salt application silicon wafer. So far grafting of diazonium salts on metals has been accomplished on iron, cobalt, nickel, platinum, palladium, zinc, copper and gold ...

  7. Azo coupling - Wikipedia

    en.wikipedia.org/wiki/Azo_coupling

    In organic chemistry, an azo coupling is an reaction between a diazonium compound (R−N≡N +) and another aromatic compound that produces an azo compound (R−N=N−R’).In this electrophilic aromatic substitution reaction, the aryldiazonium cation is the electrophile, and the activated carbon (usually from an arene, which is called coupling agent), serves as a nucleophile.

  8. Diazomethane - Wikipedia

    en.wikipedia.org/wiki/Diazomethane

    Diazomethane is an organic chemical compound with the formula CH 2 N 2, discovered by German chemist Hans von Pechmann in 1894. It is the simplest diazo compound.In the pure form at room temperature, it is an extremely sensitive explosive yellow gas; thus, it is almost universally used as a solution in diethyl ether.

  9. Hofmann–Löffler reaction - Wikipedia

    en.wikipedia.org/wiki/Hofmann–Löffler_reaction

    The Suárez modification of the Hofmann–Löffler–Freytag reaction was the basis of the new synthetic method developed by H. Togo et al. [42] [43] The authors demonstrated that various N-alkylsaccharins (N-alkyl-1,2-benzisothiazoline-3-one-1,1,-dioxides) 77 are easily prepared in moderate to good yields by the reaction of N-alkyl(o-methyl ...