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an inflammation in the middle layers of the bronchi and bronchioles; excessive production of mucus. The bronchial spasm is due to the activation of parasympathetic nervous system. Postganglionic parasympathetic fibers will release acetylcholine causing the constriction of the smooth muscle layer surrounding the bronchi.
The overactivity of the bronchioles' muscle is a result of exposure to a stimulus which under normal circumstances would cause little or no response. The resulting constriction and inflammation causes a narrowing of the airways and an increase in mucus production; this reduces the amount of oxygen that is available to the individual causing ...
The parasympathetic nervous system decreases respiration and heart rate and increases digestion. Stimulation of the parasympathetic nervous system results in: Constriction of pupils; Decreased heart rate and blood pressure; Constriction of bronchial muscles; Stimulation of digestion and gastric emptying; Increased production of saliva and mucus
M 3 receptors directly lead to airway smooth muscle contraction, i.e., an increase in airway tone, while M 2 receptors (also) expressed by airway neurons suppress the further release of acetylcholine in a negative feedback loop, wherein cholinergic parasympathetic signalling reduces further cholinergic parasympathetic signalling, which may ...
The sympathetic nervous system is described as being antagonistic to the parasympathetic nervous system. The latter stimulates the body to "feed and breed" and to (then) "rest-and-digest". The SNS has a major role in various physiological processes such as blood glucose levels, body temperature, cardiac output, and immune system function.
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The normal caliber of the bronchus is maintained by a balanced functioning of the autonomic nervous system, which both operate reflexively. The parasympathetic reflex loop consists of afferent nerve endings which originate under the inner lining of the bronchus. Whenever these afferent nerve endings are stimulated (for example, by dust, cold ...
The sympathetic nervous system is responsible for setting off the fight-or response. [3] The parasympathetic nervous system is responsible for the body's rest and digestion response. [3] In many cases, both of these systems have "opposite" actions where one system activates a physiological response and the other inhibits it.