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Short gut syndrome, short gut, intestinal failure: A piece of diseased ileum following removal by surgery. Specialty: Gastroenterology: Symptoms: Diarrhea, dehydration, malnutrition, weight loss [1] Complications: Anemia, kidney stones [2] Causes: Surgical removal of a large portion of the small intestine [1] Risk factors: Crohn's disease ...
The single leading cause for an intestinal transplant is affliction with short bowel syndrome, oftentimes a secondary condition of some other form of intestinal disease. [ 5 ] [ 6 ] Short-bowel syndrome was the cause for 73% of American intestinal transplantations in 2008, followed by functional bowel problems for 15% and other causes ...
Bile acid malabsorption was first recognized in patients with ileal disease. [22] When other causes were recognized, and an idiopathic, primary form described, [23] a classification into three types was proposed: [24] Type 1: Bile acid malabsorption, secondary to ileal resection, or ileal inflammation (e.g. in Crohn's disease)
Short bowel syndrome is a failure of absorption of nutrients due to resection of portions of the small bowel. It can be limited to a single nutrient or it can be total malabsorption. If the distal ileum is resected it commonly causes a mild form of short bowel syndrome with deficiency of only vitamin B12.
This is particularly common after surgery to remove the ileum. [69] Involvement of the duodenum and jejunum can impair the absorption of many other nutrients including folate. People with Crohn's often also have issues with small bowel bacterial overgrowth syndrome, which can produce micronutrient deficiencies. [71] [72]
As a result, huge amounts of fatty acids, which are normally absorbed in the small intestine, enter the colon, where they cause irritation of the colon wall and the secretion of excessive volumes of water and electrolytes, especially sodium and potassium, leading to diarrhea. This diarrhea is the major patient complaint and has characterized ...