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Inner ear regeneration is the biological process by which the hair cells and supporting cells (i.e. Hensen's cells and Deiters cells) of the ear proliferate (cell proliferation) and regrow after hair cell injury. This process depends on communication between supporting cells and the brain.
[5] [6] Furthermore, Hensen's cells are also able to regenerate the damaged hair cells in some vertebrates; they undergo phagocytosis to eject the dead or injured hair cells, and reproduce both new hair cells and supporting cells into the cell cycle. One of the reasons is that the supporting cells are differentiated by the embryonic hair cells ...
The cell cycle inhibitor p27kip1 has also been found to encourage regrowth of cochlear hair cells in mice following genetic deletion or knock down with siRNA targeting p27. [36] [37] Research on hair cell regeneration may bring us closer to clinical treatment for human hearing loss caused by hair cell damage or death.
Re-narrated Horizon episode, first aired in the UK in 1972. [4]We give you a behind-the-scenes look at the making of a nature film. Oxford Scientific Films Unit shows how it tackles such problems as filming a wood wasp laying its eggs inside trees, the hatching of a chick and the courtship rituals of the stickleback.
A cochlear implant is surgical implantation of a battery powered electronic medical device in the inner ear. Unlike hearing aids , which make sounds louder, cochlear implants do the work of damaged parts of the inner ear (cochlea) to provide sound signals to the brain.
Structural damage to hair cells (primarily the outer hair cells) will result in hearing loss that can be characterized by an attenuation and distortion of incoming auditory stimuli. During hair cell death 'scars' develop, which prevent potassium rich fluid of the endolymph from mixing with the fluid on the basal domain. [ 86 ]
There are two types of hair cells specific to the auditory system; inner and outer hair cells. Inner hair cells are the mechanoreceptors for hearing: they transduce the vibration of sound into electrical activity in nerve fibers, which is transmitted to the brain. Outer hair cells are a motor structure.
Boettcher cells are a special cell type located in the inner ear. Boettcher cells are polyhedral cells on the basilar membrane of the cochlea , and are located beneath Claudius cells . [ 1 ] Boettcher cells are considered supporting cells for the organ of Corti , and are present only in the lower turn of the cochlea.