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A summary of CHOP upstream and downstream pathways. The PERK-ATF4-CHOP pathway can induce apoptosis by binding to the death receptors and upregulating the expression of death receptor 4 (DR4) and DR5. CHOP also interacts with the phosphorylated transcription factor JUN to form a complex that binds to the promoter region of DR4 in lung cancer ...
"For example, the frequency of migraine attacks determines if a person has episodic or chronic migraine," Zhang tells Yahoo Life. "People with episodic migraine have less than 15 headache days/month.
Chemoimmunotherapy is chemotherapy combined with immunotherapy.Chemotherapy uses different drugs to kill or slow the growth of cancer cells; immunotherapy uses treatments to stimulate or restore the ability of the immune system to fight cancer. [1]
Dopaminergic pathways (dopamine pathways, dopaminergic projections) in the human brain are involved in both physiological and behavioral processes including movement, cognition, executive functions, reward, motivation, and neuroendocrine control. [1] Each pathway is a set of projection neurons, consisting of individual dopaminergic neurons.
The Levels of Processing model, created by Fergus I. M. Craik and Robert S. Lockhart in 1972, describes memory recall of stimuli as a function of the depth of mental processing. More analysis produce more elaborate and stronger memory than lower levels of processing. Depth of processing falls on a shallow to deep continuum.
The trisynaptic circuit or trisynaptic loop is a relay of synaptic transmission in the hippocampus.The trisynaptic circuit is a neural circuit in the hippocampus, which is made up of three major cell groups: granule cells in the dentate gyrus, pyramidal neurons in CA3, and pyramidal neurons in CA1.
For example, if one is to learn about a topic and study it in a specific location, but take their exam in a different setting, they would not have had as much of a successful memory recall as if they were in the location that they learned and studied the topic in. Encoding specificity helps to take into account context cues because of its focus ...
Information processing theory is the approach to the study of cognitive development evolved out of the American experimental tradition in psychology. Developmental psychologists who adopt the information processing perspective account for mental development in terms of maturational changes in basic components of a child's mind.