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Treatment may include dietary changes and folic acid supplements. [1] Dietary changes including eating foods high in folate such as, fruits and green leafy vegetables can help. [1] Prevention is recommended for pregnant women or those who are planning a pregnancy. [1] Folate deficiency is very rare in countries with folic acid fortification ...
A 2019 study suggested that oral B 12 is inferior to B 12 injections in severe cases, as "there is no proof in large prospective, double-blind studies that oral supplementation is as effective in reducing symptoms associated with vitamin B 12 deficiency as parenteral treatment." [153] There is risk that folic acid administered to those with ...
And folic acid, a B vitamin, is one supplement that has wide support from public health experts, even among supplement skeptics. ... deficiency that’s affecting your health — such as a B12 ...
Prolonged deficiency of vitamin B 12 leads to irreversible nervous system damage. HIV-associated vacuolar myelopathy can present with a similar pattern of dorsal column and corticospinal tract demyelination. [citation needed] It has been thought that if someone is deficient in vitamin B 12 and folic acid, the vitamin B 12 deficiency must
Folate in the form of folic acid is used to treat anemia caused by folate deficiency. [3] Folic acid is also used as a supplement by women during pregnancy to reduce the risk of neural tube defects (NTDs) in the baby. [3] [10] NTDs include anencephaly and spina bifida, among other defects.
Otherwise, methylmalonic acid accumulates, making it a marker for vitamin B 12 deficiency, among other things. Methylmalonyl coenzyme A mutase (MUT) is an isomerase enzyme that uses the AdoB 12 form and reaction type 1 to convert L-methylmalonyl-CoA to succinyl-CoA , an important step in the catabolic breakdown of some amino acids into succinyl ...