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Four things are required for caries to form: a tooth surface (enamel or dentin), caries-causing bacteria, fermentable carbohydrates (such as sucrose), and time. [20] This involves adherence of food to the teeth and acid creation by the bacteria that makes up the dental plaque. [21]
It is a meticulously formed microbial community, that is organised to a particular structure and function. [12] Plaque is rich in species, given the fact that about 1000 different bacterial species have been recognised using modern techniques. [13] A clean tooth surface would immediately be colonised by salivary pellicles, which acts as an ...
The most commonly recognised bacteria that are responsible for initiating the biofilm formation that can eventually lead to caries are streptococcus mutans and lactobacillus. [15] The key factors for virulence include their ability to metabolise glucose and similar sugars, their tolerance for a low pH environment, and their acidogenicity. [ 16 ]
Other bacteria, including Streptococcus mutans, are able to grow in these colonies. Streptococcus mutans is important, because it is associated with dental caries. [5] These bacteria produce the enzyme glucosyltransferase. Glucosyl transferase converts sucrose into exopolysaccharides. These exopolysacharides create a sticky environment that ...
Bacteria occupy the ecological niche provided by both the tooth surface and mucosal epithelium. [ 7 ] [ 8 ] Factors of note that have been found to affect the microbial colonization of the oral cavity include the pH, oxygen concentration and its availability at specific oral surfaces, mechanical forces acting upon oral surfaces, salivary and ...
S. mutans has the following surface protein antigens: glucosyltransferases, protein antigen and glucan-binding proteins. If these surface protein antigens are not present, then the bacteria is a protein antigen-defective mutant with the least susceptibility to phagocytosis therefore causing the least harm to cells. [citation needed]
Early childhood caries (ECC) is a multifactorial disease, with risk factors including but not limited to, cariogenic bacteria, diet practices and socioeconomic factors. [6] Deciduous teeth begin to erupt at 6 months of age, once visible in the oral cavity they are susceptible to tooth decay or dental caries. [1]
Teeth, saliva, and oral tissues are the major components of the oral environment in which the oral microbiome resides. Like most environments, some oral environments, such as teeth and saliva, are abiotic (non-living), and some are living, such as the host immune system or host mouth mucosal tissues- including gums, cheek ("buccal") and tongue (when present).