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The thick descending limb is less important than the thin descending limb, so often the terms "descending limb" and "thin descending limb" are used interchangeably. Some sources simply refer to a "thin limb". In this context, the thin ascending limb of loop of Henle would be included.
The descending portion of the loop of Henle is extremely permeable to water and is less permeable to ions, therefore water is easily reabsorbed here and solutes are not readily reabsorbed. The 300 mOsm/L fluid from the loop loses water to the higher concentration outside the loop and increases in tonicity until it reaches its maximum at the ...
Proximal convoluted tubule: lies in the cortex and is lined by 'simple cuboidal epithelium with brush borders' which greatly increase surface area for absorption. Loop of Henle: lies in the medulla and is U-shaped (similar to a hair-pin) Descending limb of loop of Henle: one segment of equal thickness
Equilibration: Since the descending limb of the loop of Henle consists of very leaky epithelium, the fluid inside the descending limb becomes hyperosmolar. [citation needed] Shift: The movement of fluid through the tubules causes the hyperosmotic fluid to move further down the loop. Repeating many cycles causes fluid to be near isosmolar at the ...
Thin descending loop of Henle: H 2 O: Reabsorbs via medullary hypertonicity and makes urine hypertonic. Thick ascending loop of Henle: Na + (10–20%), K +, Cl −; indirectly induces para cellular reabsorption of Mg 2+, Ca 2+ This region is impermeable to H 2 O and the urine becomes less concentrated as it ascends. Early distal convoluted ...
They enter the medulla, and surround the loop of Henle. Whereas the peritubular capillaries surround the cortical parts of the tubules, the vasa recta go into the medulla and are closer to the loop of Henle, [1] [2] and leave to ascend to the cortex. [3] [4]
This illustration demonstrates the normal kidney physiology, including the Proximal Convoluted Tubule (PCT), Loop of Henle, and Distal Convoluted Tubule (DCT). It also includes illustrations showing where some types of diuretics act, and what they do. Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney.
Both limbs of the loop of Henle are lined with the simple squamous epithelium. [2] Their main function is to regulate the levels of water and solutes in the primary urine . The basement membrane of the thin limb in humans has very uniform nodular thickenings that form a network that surrounds the tubule and acts as a support structure that is ...