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Supercritical fluids act as a new medium for the generation of novel crystalline forms of APIs (Active Pharmaceutical Ingredients) named as pharmaceutical cocrystals. Supercritical fluid technology offers a new platform that allows a single-step generation of particles that are difficult or even impossible to obtain by traditional techniques.
Chromatography software is called also Chromatography Data System. [1] It is located in the data station of the modern liquid, gas or supercritical fluid chromatographic systems. This is a dedicated software connected to an hardware interface within the chromatographic system, which serves as a central hub for collecting, analyzing, and ...
The supercritical solvent is passed into a vessel at lower pressure than the extraction vessel. The density, and hence dissolving power, of supercritical fluids varies sharply with pressure, and hence the solubility in the lower density CO 2 is much lower, and the material precipitates for collection. It is possible to fractionate the dissolved ...
Supercritical fluid chromatography (SFC) [1] is a form of normal phase chromatography that uses a supercritical fluid such as carbon dioxide as the mobile phase. [2] [3] It is used for the analysis and purification of low to moderate molecular weight, thermally labile molecules and can also be used for the separation of chiral compounds.
Non ideal compressible fluid dynamics (NICFD), or non ideal gas dynamics, is a branch of fluid mechanics studying the dynamic behavior of fluids not obeying ideal-gas thermodynamics. It is for example the case of dense vapors , supercritical flows and compressible two-phase flows .
Waters Corporation is an American publicly traded analytical laboratory instrument and software company headquartered in Milford, Massachusetts. The company employs more than 7,800 [2] people, with manufacturing facilities located in Milford, Taunton, Massachusetts; Wexford, Ireland and Wilmslow, [3] Cheshire.
Supercritical carbon dioxide can be used as a solvent in dry cleaning. [4] Supercritical carbon dioxide is used as the extraction solvent for creation of essential oils and other herbal distillates. [5] Its main advantages over solvents such as hexane and acetone in this process are that it is non-flammable and does not leave toxic residue.
However, different criteria still allow to distinguish liquid-like and more gas-like states of a supercritical fluid. These criteria result in different boundaries in the pT plane. These lines emanate either from the critical point, or from the liquid–vapor boundary (boiling curve) somewhat below the critical point.