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Every year, millions of women get mammograms to screen for breast cancer. About 10% of them are called back for further testing. And 7% to 12% of those women receive a false-positive result ...
Worldwide, the rate of infection with herpes simplex virus—counting both HSV-1 and HSV-2—is around 90%. [1] Although many people infected with HSV develop labial or genital lesions ( herpes simplex ), the majority are either undiagnosed or display no physical symptoms—individuals with no symptoms are described as asymptomatic or as having ...
One consequence of the high false positive rate in the US is that, in any 10-year period, half of the American women screened receive a false positive mammogram. False positive mammograms are costly, with over $100 million spent annually in the U.S. on follow-up testing and treatment. They also cause women unneeded anxiety. As a result of the ...
Herpes simplex virus 1 (cold sores) and 2 (genital herpes) (HSV-1 and HSV-2), also known by their taxonomic names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. [1] [2] Both HSV-1 and HSV-2 are very common and ...
The log diagnostic odds ratio can also be used to study the trade-off between sensitivity and specificity [5] [6] by expressing the log diagnostic odds ratio in terms of the logit of the true positive rate (sensitivity) and false positive rate (1 − specificity), and by additionally constructing a measure, :
Mammography overall has a false-positive rate of approximately 10%. [12] It has a false-negative (missed cancer) rate of between 7 and 12 percent. [13] This is partly due to dense tissues obscuring the cancer and the fact that the appearance of cancer on mammograms has a large overlap with the appearance of normal tissues. Additionally ...
The false positive rate (FPR) is the proportion of all negatives that still yield positive test outcomes, i.e., the conditional probability of a positive test result given an event that was not present. The false positive rate is equal to the significance level. The specificity of the test is equal to 1 minus the false positive rate.
A daily swab of the genital area was self-collected for Human alphaherpesvirus 2 detection by polymerase chain reaction, to compare the effect of valaciclovir versus placebo on asymptomatic viral shedding in immunocompetent, seropositive subjects without a history of symptomatic genital herpes infection. The study found that valaciclovir ...