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These regional variants of ALS can only be considered as a diagnosis should the initial symptoms fail to spread to other spinal cord regions for an extended period of time (at least 12 months). [28] Flail arm syndrome is characterized by lower motor neuron damage affecting the arm muscles, typically starting with the upper arms symmetrically ...
Therefore, the diagnosis occurs as the result of eliminating other possible causes of the symptoms and by an extended observation period. [ 10 ] Like ALS, diagnosing PLS is a diagnosis of exclusion, as there is no one test that can confirm a diagnosis of PLS.
Symptoms of motor neuron diseases can be first seen at birth or can come on slowly later in life. Most of these diseases worsen over time; while some, such as ALS, shorten one's life expectancy, others do not. [2] Currently, there are no approved treatments for the majority of motor neuron disorders, and care is mostly symptomatic. [2]
What you need to know about the signs and symptoms, causes, and treatment options for the rare neurological disease.
ALS can manifest in people differently, but it usually starts with weakness that spreads or gets worse over time, according to the Mayo Clinic. Here are some of the symptoms of this fatal disease.
After experiencing two miscarriages prior to the onset of her father’s first ALS symptoms, she began sharing her struggles online to find a community of others who were trying to conceive.
Public awareness of the disease gained prominence upon the diagnosis of baseball player Lou Gehrig, whose name would become an alternative title for the disease. Astrophysicist Stephen Hawking, whose ALS was diagnosed in 1963, had the disease for 55 years, the longest recorded time one had the disease. He died at the age of 76 in 2018.
According to the NIH, early symptoms of ALS may include: Muscle weakness affecting an arm, leg or the diaphragm. Twitching of the muscles in the arms, legs, shoulders or tongue.