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Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a class of drugs that are used to suppress abnormally fast rhythms (tachycardias), such as atrial fibrillation, supraventricular tachycardia and ventricular tachycardia. Many attempts have been made to classify antiarrhythmic agents.
Procainamide (PCA) is a medication of the antiarrhythmic class used for the treatment of cardiac arrhythmias. It is a sodium channel blocker of cardiomyocytes; thus it is classified by the Vaughan Williams classification system as class Ia. In addition to blocking the I Na current, it inhibits the I Kr rectifier K+ current. [1]
Reverse use dependent drugs that slow heart rate (such as quinidine) can be less effective at high heart rates. [11] The refractoriness of the ventricular myocyte increases at lower heart rates . [ citation needed ] This increases the susceptibility of the myocardium to early Afterdepolarizations (EADs) at low heart rates.
Heart rate can also be lowered with the help of medication, says Nicole Weinberg, M.D., board-certified cardiologist at Providence Saint John’s Health Center. “Aside from cardiac-specific ...
Amiodarone has been used both in the treatment of acute life-threatening arrhythmias as well as the long-term suppression of arrhythmias. [13] Amiodarone is commonly used to treat different types of abnormal heart rhythms, such as atrial arrhythmias (supraventricular arrhythmias) and ventricular arrhythmias.
Digoxin is in the cardiac glycoside family of medications. [4] It was first isolated in 1930 from the foxglove plant, Digitalis lanata. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] In 2021, it was the 241st most commonly prescribed medication in the United States, with more than 1 million prescriptions. [10 ...
Diltiazem, sold under the brand name Cardizem among others, is a nondihydropyridine calcium channel blocker medication used to treat high blood pressure, angina, and certain heart arrhythmias. [9] It may also be used in hyperthyroidism if beta blockers cannot be used. [9] It is taken by mouth or given by injection into a vein. [9]
Patients with first-degree AV block do not have any resulting severe or life-threatening symptoms, such as symptomatic bradycardia or hypotension, and, thus, do not require treatment. [1] Similarly, patients with second-degree Mobitz I AV block rarely develop life-threatening symptoms, and patients who are asymptomatic do not require treatment ...