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GHB is a central nervous system depressant used as an intoxicant. [29] It has many street names. Its effects have been described as comparable with ethanol (alcohol) and MDMA use, such as euphoria, disinhibition, enhanced libido and empathogenic states. A review comparing ethanol to GHB concluded that the dangers of the two drugs were similar. [30]
The US label for sodium oxybate has a black box warning because it is a central nervous system depressant (CNS depressant) and for its potential for abuse.Other potential adverse side effects include respiratory depression, seizures, coma, and death, especially when it is taken in combination with other CNS depressants such as alcohol.
GBL is a prodrug of GHB (naturally produced) and its recreational use comes entirely as a result of this. [33] GBL overdose can cause irrational behavior, severe sickness, coma and death. [34] To bypass GHB restriction laws, home synthesis kits were introduced to transform GBL and/or 1,4-B into GHB.
The function of the GHB receptor appears to be quite different from that of the GABA B receptor. It shares no sequence homology with GABA B, and administration of mixed GHB/GABA B receptor agonists, along with a selective GABA B antagonist or selective agonists for the GHB receptor which are not agonists at GABA B, do not produce a sedative effect, instead causing a stimulant effect, followed ...
In 2011, street prices in the United States ranged between $10 and $30 per tablet when purchased in small quantities. [6] Larger retail purchases cost between $200 and $500 per gram. Wholesale purchases of 2C-B would lower the price ($100 to $300 per gram in 2001, $30 to $100 on the darknet in 2020).
Elon Musk said he is “almost always” sober during his late-night — or, in some cases, very early morning — posting sessions on his social media platform, X.
StreetPrices was founded in October 1997, [1] [2] making it the third price comparison service website, behind PriceWatch (1995) and ComputerESP/uVision (1996). StreetPrices was the first site to offer price graphs and price alerts (both released by December 1998), [3] and was listed in the Consumer Reports Buying Guide every year in which they listed price comparison services by name. [4]
An assortment of several designer drugs. Designer drugs are structural or functional analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug while avoiding detection or classification as illegal.