Ads
related to: afp tumor marker liver cirrhosis
Search results
Results From The WOW.Com Content Network
The L3 isoform is specific to malignant tumors and its detected presence can serve to identify patients whom need increased monitoring for the development of HCC in high risk populations (i.e. chronic hepatitis B and C and/or liver cirrhosis). AFP-L3% is now being considered as a tumor marker for the North American demographic.
Like any elevated tumor marker, elevated AFP by itself is not diagnostic, only suggestive. Tumor markers are used primarily to monitor the result of a treatment (e.g. chemotherapy). If levels of AFP go down after treatment, the tumor is not growing. In the case of babies, after treatment AFP should go down faster than it would normally. A ...
Barcelona Clinic Liver Cancer (BCLC) Staging System. The prognosis of HCC is affected by the staging of the tumor, the liver's function due to the effects of chronic liver disease and cirrhosis as well as the person's physical performance status. [48] A number of staging classifications for HCC are available.
The usual markers for liver disease – aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase – are often normal or only slightly elevated. FLC often does not produce alpha fetoprotein (AFP), a widely used marker for conventional hepatocellular carcinoma.
L1 is the form associated most commonly with liver disease and L3 is most commonly associated with malignant tumors. AFP-L3 can be used to detect hepatocellular carcinoma early on when compared to overall AFP levels. Liver cirrhosis can produce more AFP but a concentration over 200 can indicate hepatocellular carcinoma. [12]
Of note, AFP is most useful for monitoring if liver cancers come back after treatment rather than for initial diagnosis. [17] Cholangiocarcinoma can be detected with these commonly used tumor markers: carbohydrate antigen 19-9 (CA 19–9), carcinoembryonic antigen (CEA) and cancer antigen 125 . These tumor markers are found in primary liver ...
Ads
related to: afp tumor marker liver cirrhosis