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Norgestimate, sold under the brand name Ortho Tri-Cyclen among others, is a progestin medication which is used in birth control pills for women and in menopausal hormone therapy. [ 1 ] [ 3 ] [ 4 ] [ 5 ] The medication is available in combination with an estrogen and is not available alone. [ 6 ]
In 1989, the FDA approved Ortho Cyclen containing the first new progestin (norgestimate) approved in over 20 years in the United States. In 1992, Ortho introduced Ortho Tri-Cyclen in the United States, which in 1996 became the first oral contraceptive with an FDA-approved non-contraceptive indication (treatment of moderate acne).
These include Ortho Tri-Cyclen, Estrostep, Beyaz, and YAZ. [65] [66] [67] Hirsutism is the growth of coarse, dark hair where women typically grow only fine hair or no hair at all. [68] This hair growth on the face, chest, and abdomen is also mediated by higher levels or action of androgens.
250 μg norgestimate (UK: Cilest, Janssen-Cilag; US: Ortho Cyclen, Ortho-McNeil; MonoNessa, Watson; Sprintec, Barr; Sweden: Amorest [8]) 2000 μg cyproterone acetate: only approved for severe acne or severe hirsutism in the UK (AU, RU: Diane-35, UK: Dianette, Bayer) 50 μg mestranol (equivalent to 35 μg ethinylestradiol)
This is a list of progestogens (progesterone and progestins) and formulations that are approved by the FDA Tooltip Food and Drug Administration in the United States. . Progestogens are used as hormonal contraceptives, in hormone replacement therapy for menopausal symptoms, and in the treatment of gynecological
The first birth control patch, "Ortho Evra" was first introduced in 2002. [51] In 2014, a generic version of Ortho Evra was released and called "Xulane". [ 52 ] In 2020, the FDA approved Twirla, a low-dose transdermal combined hormonal contraceptive.
Norelgestromin is available only as a transdermal contraceptive patch in combination with ethinyl estradiol. [6] The Ortho Evra patch is a 20 cm 2, once-weekly adhesive that contains 6.0 mg norelgestromin and 0.6 mg ethinyl estradiol and delivers 200 μg/day norelgestromin and 35 μg/day ethinyl estradiol.
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