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  2. Lipase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Lipase_inhibitors

    Lipase inhibitors can be found naturally in plants and can also be produced as pharmaceutical drugs.Some lipase inhibitors have been identified in Panax ginseng. [5] [6] Some active compounds with chalcone scaffold found in Glycyrrhiza glabra, Cassia mimosoides, Glycyrrhiza uralensis, Boesenbergia rotunda, apples and Morus alba also had strong effect against lipase.

  3. Discovery and development of gastrointestinal lipase inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Lipase inhibitors belong to a drug class that is used as an antiobesity agent. Their mode of action is to inhibit gastric and pancreatic lipases, enzymes that play an important role in the digestion of dietary fat. [2] Lipase inhibitors are classified in the ATC-classification system as A08AB (peripherally acting antiobesity products). [3]

  4. Lipoprotein lipase - Wikipedia

    en.wikipedia.org/wiki/Lipoprotein_lipase

    Lipoprotein lipase has been shown to interact with LRP1. [ 51 ] [ 52 ] [ 53 ] It is also a ligand for α2M , GP330 , and VLDL receptors. [ 23 ] LPL has been shown to be a ligand for LRP2 , albeit at a lower affinity than for other receptors; however, most of the LPL-dependent VLDL degradation can be attributed to the LRP2 pathway. [ 23 ]

  5. How Does Topirmate for Weight Loss Work? - AOL

    www.aol.com/does-topirmate-weight-loss-135700587...

    In a 2012 study, for example, 385 participants with obesity followed a lifestyle program and took either a placebo or topiramate for 24 weeks. Those on topiramate started on a daily dose of 16mg ...

  6. ANGPTL3 - Wikipedia

    en.wikipedia.org/wiki/ANGPTL3

    Angptl3 also acts as dual inhibitor of lipoprotein lipase (LPL) and endothelial lipase (EL), [7] thereby increasing plasma triglyceride, LDL cholesterol and HDL cholesterol in mice and humans. [7] ANGPTL3 inhibits endothelial lipase hydrolysis of HDL-phospholipid (PL), thereby increasing HDL-PL levels.

  7. Orlistat - Wikipedia

    en.wikipedia.org/wiki/Orlistat

    Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity.Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake.

  8. Alipogene tiparvovec - Wikipedia

    en.wikipedia.org/wiki/Alipogene_tiparvovec

    Alipogene tiparvovec, sold under the brand name Glybera, is a gene therapy treatment designed to reverse lipoprotein lipase deficiency (LPLD), a rare recessive disorder, due to mutations in LPL, which can cause severe pancreatitis. [1]

  9. What is a beta blocker? Why they are vital to those with ...

    www.aol.com/beta-blocker-why-vital-those...

    Like any drug, taking beta blockers comes with side effects. Churchwell said they can cause bronchial constriction, which can be a problem for people with chronic lung disease, asthma and diabetes.