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Schamberg's disease, (also known as "progressive pigmentary dermatosis of Schamberg", [1] "purpura pigmentosa progressiva" (PPP), [1] and "Schamberg's purpura" [1]) is a chronic discoloration of the skin found in people of all ages, usually only affecting the feet, legs or thighs or a combination.
Acral lentiginous melanoma (ALM) is a type of skin cancer. [6] It typically begins as a uniform brownish mark before becoming darker and wider with a blurred, irregular border. ALM is most frequently seen on the foot of a person with darker skin but can also be found in non-sun exposed areas such as the palms, soles, and under finger and ...
A plantar wart is a wart occurring on the bottom of the foot or toes. [5] Its color is typically similar to that of the skin. [2] Small black dots often occur on the surface. [5] One or more may occur in an area. [2] They may result in pain with pressure such that walking is difficult. [2] They are caused by the human papillomavirus (HPV). [2]
Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [10] cSCC typically presents as a hard lump with a scaly surface, though it may also present as an ulcer. [1]
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Most minor cases of foot pain can be responded to by home care treatments. However, when severe pain is present, medical attention is required as it is a disabling condition. If foot pain is not treated in time, it can lead to long-term disability and continuing damage to the foot. [2]
Recurrent cancers are much harder to cure, with a higher recurrence rate with any method of treatment. Although basal-cell carcinoma rarely metastasizes, it grows locally with invasion and destruction of local tissues. The cancer can impinge on vital structures like nerves and result in loss of sensation or loss of function or rarely death. The ...
If the cancer has spread to other areas of the body, chemotherapy may be used to shrink tumors and reduce the pain and discomfort they cause, but is unlikely to eradicate the disease. A combination of docetaxel and gemcitabine could be an effective chemotherapy regimen in patients with advanced soft-tissue sarcoma.