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A three-drug regimen of rifampicin, dapsone, and clofazimine is recommended for all people with leprosy, for six months for paucibacillary leprosy and 12 months for multibacillary leprosy. [9] Multidrug therapy (MDT) remains highly effective, and people are no longer infectious after the first monthly dose. [4]
They concluded that a single dose of a combination of rifampicin, ofloxacin and minocycline is an acceptable and cost-effective alternative regimen for the treatment of single-lesion paucibacillary leprosy and the duration of the standard regimen for multibacillary leprosy could be shortened to 12 months.
Mycobacterium leprae (also known as the leprosy bacillus or Hansen's bacillus) is one [a] of the two species of bacteria that cause Hansen's disease (leprosy), [1] a chronic but curable infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles.
Current recommendations for the treatment of leprosy suggest multidrug regimens rather than monotherapy because such a regimen has proven to be more effective, delays the emergence of resistance, prevents relapse, and shortens the duration of therapy. Established agents used in the treatment of leprosy are dapsone, clofazimine, and rifampicin ...
Ridley-Jopling classification of leprosy, textbook Handbook of Leprosy and medical papers including leprosy stigma William Jopling (2 March 1911 – 21 August 1997) [ 1 ] was an Italian-born British leprologist who together with D. S. Ridley proposed the Ridley-Jopling classification of leprosy (1962), and wrote the widely read textbook ...
A bishop instructing clerics with leprosy from Omne Bonum by 14th-century clerk James le Palmer (British Library, MS Royal 6 E VI, vol. 2, fol. 301ra). Medieval depictions of leprosy commonly showed the patient to have red spots. [30] Alternative treatments included scarification with or without the addition of irritants including arsenic and ...
[1]: 345 Tuberculoid leprosy is characterized by the formation of epithelioid cell granulomas consisting of a large number of epithelioid cells. In this form of leprosy, Mycobacterium leprae are either absent from the lesion or occur in very small numbers. This type of leprosy is the most benign and the least contagious. [2] [3]
Spinalonga on Crete, Greece, one of the last leprosy colonies in Europe, closed in 1957. A leper colony, also known by many other names, is an isolated community for the quarantining and treatment of lepers, people suffering from leprosy.