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Inositol nicotinate is generally safe when taken by mouth, but possible side effects include: Stomach upset; Intestinal gas; Nausea; Liver damage (similar to other niacin products) [1] It is marketed as "no-flush" niacin, but research suggests that the lack of flushing may be due to its limited conversion to active niacin. [4]
Liver damage [4] Guarana: Paullinia cupana: Agitation and insomnia [3] Guar gum: guaran: Obstruction of gastrointestinal tract [5] Gugulipid: guggal, guggul, Mukul myrrh tree Commiphora mukul "Headache, nausea, hiccups, diminished efficacy of other cardiovascular drugs including diltiazem and propranolol" [3] Hawthorn
As with niacin and related drugs, the most common adverse effects are flushing (associated with prostaglandin D 2 [2]) and gastrointestinal disturbances such as indigestion, which occur in at least 10% of patients. [1] Flushing can be reduced by taking aspirin 20 to 30 minutes before taking acipimox. Palpitations have also been described.
Similar to statins, the risk of muscle damage exists. Nicotinic acid, like fibrates, is also well suited for lowering triglycerides by 20–50%. It may also lower LDL by 5–25% and increase HDL by 15–35%. Niacin may cause hyperglycemia and may also cause liver damage. The niacin derivative acipimox is also associated with a modest decrease ...
Supplements That Damage the Liver The supplements the study mentioned include: Ashwagandha , used to support the nervous and endocrine systems; improve sleep; and boost mood, energy and immune levels
Laropiprant is a prostaglandin D2 binding drug shown to reduce niacin-induced vasodilation and flushing side effects. [28] [72] [73] A clinical trial showed no additional efficacy of Tredaptive in lowering cholesterol when used together with other statin drugs, but did show an increase in other side effects. [74]
Like other medications for the treatment of (ED), Cialis — and its generic version, tadalafil — can cause adverse effects at first. Fortunately, most tadalafil side effects are mild and ...
In chronic liver diseases such as cirrhosis, bile acids may deposit in the skin, causing pruritus (itching). Hence, bile acid sequestrants may be used for the prevention of pruritus in patients with chronic liver disease. [10] Bile acid sequestrants may also be used to treat hyperthyroidism as an adjunct therapy.