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Probenecid, also sold under the brand name Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia . Probenecid was developed as an alternative to caronamide [ 1 ] to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and ...
Streptococcal pharyngitis, also known as streptococcal sore throat (strep throat), is pharyngitis (an infection of the pharynx, the back of the throat) caused by Streptococcus pyogenes, a gram-positive, group A streptococcus. [9] [10] Common symptoms include fever, sore throat, red tonsils, and enlarged lymph nodes in the front of the neck.
A case of strep throat. Streptococcal pharyngitis or strep throat is caused by a group A beta-hemolytic streptococcus (GAS). [20] It is the most common bacterial cause of cases of pharyngitis (15–30%). [19] Common symptoms include fever, sore throat, and large lymph nodes. It is a contagious infection, spread by close contact with an infected ...
It was a retrospective study (2008–2010) and looked at 441 children who attended a Belgian hospital emergency department and had a throat swab taken. It concluded that the Centor criteria are ineffective in predicting the presence of Group A beta-haemolytic streptococcus (i.e. antibiotic treatment-worthy) on throat swab cultures in children. [4]
It is not known whether antibiotics are effective for preventing recurrent sore throat. [14] There is only limited evidence that a hot drink can help alleviate a sore throat, and other common cold and influenza symptoms. [15] If the sore throat is unrelated to a cold and is caused by, for example, tonsillitis, a cold drink may be helpful. [16]
A rapid strep test may assist a clinician in deciding whether to prescribe an antibiotic to a person with pharyngitis, a common infection of the throat. [1] Viral infections are responsible for the majority of pharyngitis, but a significant proportion (20% to 40% in children and 5% to 15% in adults) is caused by bacterial infection. [2]
Post-streptococcal glomerulonephritis (PSGN) is an uncommon complication of either a strep throat or a streptococcal skin infection. It is classified as a type III hypersensitivity reaction. Symptoms of PSGN develop within 10 days following a strep throat or 3 weeks following a GAS skin infection. PSGN involves inflammation of the kidney.
[1] [5] Confirmation may be by a throat swab or rapid strep test. [1] [5] Treatment efforts involve improving symptoms and decreasing complications. [5] Paracetamol (acetaminophen) and ibuprofen may be used to help with pain. [1] [5] If strep throat is present the antibiotic penicillin by mouth is generally recommended.