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It has a bioavailability of 20-40%, reaches peak plasma concentration in about 45 minutes, and in healthy subjects has an average half-life of 5 hours (observed range 2 - 10 hours). [7] Scopolamine is primarily metabolized by the CYP3A4 enzyme, and Grapefruit juice decreases metabolism of scopolamine, consequently increasing plasma concentration.
For example, the medical sciences refer to the biological half-life of drugs and other chemicals in the human body. The converse of half-life (in exponential growth) is doubling time. The original term, half-life period, dating to Ernest Rutherford's discovery of the principle in 1907, was shortened to half-life in the early 1950s. [1]
Hyoscine butylbromide, also known as scopolamine butylbromide [4] and sold under the brandname Buscopan among others, [5] is an anticholinergic medication used to treat abdominal pain, esophageal spasms, bladder spasms, biliary colic, [6] and renal colic. [7] [8] It is also used to improve excessive respiratory secretions at the end of life. [9]
Rectal temperature is expected to be approximately 1 °F (0.56 °C) higher than an oral temperature taken on the same person at the same time. Ear thermometers measure temperature from the tympanic membrane using infrared sensors and also aim to measure core body temperature, since the blood supply of this membrane is directly shared with the ...
A medical thermometer or clinical thermometer is a device used for measuring the body temperature of a human or other animal. The tip of the thermometer is inserted into the mouth under the tongue (oral or sub-lingual temperature), under the armpit (axillary temperature), into the rectum via the anus (rectal temperature), into the ear (tympanic temperature), or on the forehead (temporal ...
Temperature increase causes the fluid to expand, so the temperature can be determined by measuring the volume of the fluid. Such thermometers are usually calibrated so that one can read the temperature simply by observing the level of the fluid in the thermometer. Another type of thermometer that is not really used much in practice, but is ...
"Thermography devices have been cleared by the FDA for use as an adjunct, or additional, tool for detecting breast cancer." The FDA says it is not effective for any kind of medical screening. [ 11 ] The AAT has published several Position Papers, including statements on Breast Thermography that clearly delineate its utility as an adjudicative ...
The Arctic Sun has adhesive gel pads which stick to a patient's body, and cover only a portion of a patient's body to leave most of the body free for augmenting medical procedures. The device operates under negative pressure and circulates water through the adhesive pads at a temperature between 4–42 °C (39–108 °F).